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Phenotypes Associated with This Genotype
Genotype
MGI:3521786
Allelic
Composition		 Plaurtm1Jld/Plaurtm1Jld
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plaurtm1Jld mutation (2 available); any Plaur mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:63134 )
N
• 14 days after bleomycin treatment, wild-type and mutant mice display a similar increase in lung collagen (hydroxyproline) content
• 14 days after bleomycin treatment, wild-type and mutant mice show similar focal areas of pulmonary fibrosis surrounded by normal alveoli; no intra-alveolar hemorrhage or early deaths are observed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory