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Phenotypes Associated with This Genotype
Genotype
MGI:3525491
Allelic
Composition		 Mmp7tm1Lmm/Mmp7tm1Lmm
Timp1tm1Pds/Timp1tm1Pds
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp7tm1Lmm mutation (1 available); any Mmp7 mutation (21 available)
Timp1tm1Pds mutation (1 available); any Timp1 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to bacterial infection ( J:94836 )
• bacterial clearance following corneal infection is increased compared to wild-type mice, however clearance is decreased compared to Timp1 single homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory