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Phenotypes Associated with This Genotype
Genotype
MGI:3525497
Allelic
Composition		 Mmp2tm1Ito/Mmp2tm1Ito
Timp1tm1Pds/Timp1tm1Pds
Genetic
Background		 either: (involves: 129S4/SvJae) or (involves: C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp2tm1Ito mutation (1 available); any Mmp2 mutation (25 available)
Timp1tm1Pds mutation (1 available); any Timp1 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to bacterial infection ( J:94836 )
• resistance to corneal infection is similar to Timp1 single homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory