Phenotypes for Strap MGI:3527250 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Strap^{Gt(ROSA)71Sor}/Strap^{Gt(ROSA)71Sor}
Genetic Background	involves: 129S4/SvJaeSor

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Strap^{Gt(ROSA)71Sor} mutation (1 available); any Strap mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:95727 )

• homozygotes die between E10.5 and E12.5

cardiovascular system

abnormal angiogenesis ( J:95727 )

abnormal heart development ( J:95727 )

embryo

abnormal embryo turning ( J:95727 )

abnormal neural tube closure ( J:95727 )

• defects in neural tube closure are seen

abnormal somite development ( J:95727 )

nervous system

abnormal neural tube closure ( J:95727 )

• defects in neural tube closure are seen

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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