Phenotypes Associated with This Genotype

Genotype
MGI:3529279

• Allelic Composition: Fgf9^tm1Dor/Fgf9^tm1Dor
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart development ( J:95803 )

• individual cardiomyoblasts appear larger and premature differentiation of cardiomyoblasts is seen

increased heart atrium size ( J:95803 )

• at E12.5 the atria are enlarged

heart hypoplasia ( J:95803 )

• at E12.5 the hearts are smaller with a disproportionate loss of tissue at the apex of the heart and in the regions around the interventricular groove, however at E18.5 the patterning of the ventricles, septum, valves, and outflow tract are normal

dilated heart left ventricle ( J:95803 )

• biventricular dilation is seen in newborn mutants

dilated heart right ventricle ( J:95803 )

• biventricular dilation is seen in newborn mutants

abnormal fetal cardiomyocyte proliferation ( J:95803 )

• decreased myocardial proliferation is seen at the apex of the heart and in the regions around the interventricular groove, however no significant difference in the levels of apoptosis is seen

muscle

abnormal fetal cardiomyocyte proliferation ( J:95803 )

• decreased myocardial proliferation is seen at the apex of the heart and in the regions around the interventricular groove, however no significant difference in the levels of apoptosis is seen

cellular

abnormal fetal cardiomyocyte proliferation ( J:95803 )

• decreased myocardial proliferation is seen at the apex of the heart and in the regions around the interventricular groove, however no significant difference in the levels of apoptosis is seen