Phenotypes Associated with This Genotype

Genotype
MGI:3574580

• Allelic Composition: Phb2^tm1Katz/Phb2⁺
• Genetic Background: 129S6/SvEvTac-Bcap37^tm1Katz

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal uterus morphology ( J:96817 )

♀ • the apical surface of the luminal epithelium in the uteri of estradiol treated females was more convoluted than the smooth apical surface in wildtype and showed luminal epithelium hyperproliferation

increased uterus weight ( J:96817 )

♀ • females treated with estradiol (E2) for 4 days had a 40% increase in uterine weight

abnormal litter size ( J:96817 )

• exhibited smaller litter sizes than on a mixed 129S6/SvEvTac and C57BL/6 background

• litter size of the second-generation mice were reduced significantly from those of the first-generation mice (4.1 vs 6.1 pups)