About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3576492
Allelic
Composition		 Apex1tm1Ecf/Apex1tm1Ecf
Genetic
Background		 either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apex1tm1Ecf mutation (0 available); any Apex1 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:70397 )
• embryos undetected at E7.5
• maternal antioxidant-enriched diet did not rescue lethality or increase the life expectancey of the embryos

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory