Phenotypes Associated with This Genotype

Genotype
MGI:3577103

• Allelic Composition: Rbbp8^tm1Whl/Rbbp8⁺
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased tumor-free survival time ( J:97648 )

• heterozygotes die around day 625 with multiple tumors, wild-type littermates die around day 780

neoplasm

increased lymphoma incidence ( J:97648 )

• multiple tumors, predominantly large lymphomas of both B and T cells are seen in older heterozygotes

• tumors all retain a wild-type copy of Rbbp8