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Phenotypes Associated with This Genotype
Genotype
MGI:3584148
Allelic
Composition		 Cpa3tm1Hrr/Cpa3tm1Hrr
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cpa3tm1Hrr mutation (0 available); any Cpa3 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal mast cell morphology ( J:99367 )
• peritoneal mast cells retain immature histochemical and biochemical hallmarks unlike wild-type cells; however the numbers of peritoneal and skin mast cells, stimulated release of hexosaminidase and histamine, and local passive cutaneous anaphylaxis are normal

hematopoietic system
abnormal mast cell morphology ( J:99367 )
• peritoneal mast cells retain immature histochemical and biochemical hallmarks unlike wild-type cells; however the numbers of peritoneal and skin mast cells, stimulated release of hexosaminidase and histamine, and local passive cutaneous anaphylaxis are normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory