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Phenotypes Associated with This Genotype
Genotype
MGI:3589284
Allelic
Composition		 Pitx2tm2Sac/Pitx2tm2Sac
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pitx2tm2Sac mutation (0 available); any Pitx2 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
adenohypophysis hypoplasia ( J:73774 )
• profound anterior pituitary gland hypoplasia is seen; however the infundibulum appears normal

nervous system
adenohypophysis hypoplasia ( J:73774 )
• profound anterior pituitary gland hypoplasia is seen; however the infundibulum appears normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory