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Phenotypes Associated with This Genotype
Genotype
MGI:3606610
Allelic
Composition		 S1pr4tm1Dgen/S1pr4+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
S1pr4tm1Dgen mutation (1 available); any S1pr4 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased prepulse inhibition ( J:101679 )
• significantly decreased prepulse inhibition when compared with age- and gender-matched wild-type control mice
• heterozygous mice had lower average PPI scores when a 120 db startling stimulus was preceded by a 90 db prepulse

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory