Analysis Tools
behavior/neurological
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• mice exhibit normal anxiety-related behavior an elevated plus maze and light-dark test
• mice exhibit normal locomotor activity
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• mice exhibit increased immobility in a forced swim test compared with wild-type mice
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• mice swim faster than wild-type mice
• mice use either one or both front paws sparingly and for steering purposes only unlike wild-type mice
• mice use their tail for propulsion unlike wild-type mice
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• mice exhibit a shorter latency to fall from a rotarod than wild-type mice
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