Phenotypes Associated with This Genotype

Genotype
MGI:3609859

• Allelic Composition: Rgs7^tm1Lex/Rgs7^tm1Lex
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:103485 )

• seen in an open field test

decreased locomotor activity ( J:103485 )

• seen in an open field test

homeostasis/metabolism

impaired glucose tolerance ( J:103485 )

• seen in homozygous males

vision/eye

abnormal rod electrophysiology ( J:150122 )

• scotopic b-wave electroretinogram responses are delayed compared to in wild-type mice

• negative-scotopic threshold response is reduced compared to in wild-type mice

• however, photoreceptor-derived a-waves are normal