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Phenotypes Associated with This Genotype
Genotype
MGI:3612382
Allelic
Composition
Gria2tm2Rsp/Gria2+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria2tm2Rsp mutation (1 available); any Gria2 mutation (76 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 20% lethality

nervous system
• AMPA receptors have a 2-fold increase in calcium permeability in CA1 pyramidal cells, but the lack of current rectification is comparable to wild-type responses


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory