growth/size/body
• young mice grow more slowly than controls, but no differences in body size are seen in adult mice
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behavior/neurological
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• a defect in feeding and nursing ability is seen in females
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integument
sparse hair
(
J:94345
)
• coat shows scant hair
|
• at 4.5 days of age, hair follicle number and arrangement appears normal
• at 2 months of age, a reduced number of hair follicles are present and some exhibit keratosis
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• hyperkeratosis of the epidermis is apparent at 2 months of age
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wrinkled skin
(
J:94345
)
• obvious skin wrinkles appear 3-4 days after birth
|