Phenotypes for Ercc1 MGI:3617389 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ercc1^tm1Dwm/Ercc1⁺
Genetic Background	involves: 129P2/OlaHsd * BALB/c

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ercc1^tm1Dwm mutation (0 available); any Ercc1 mutation (28 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

liver/biliary system

abnormal liver physiology ( J:15422 )

decreased liver function ( J:15422 )

• an increase in alanine aminotransferase activity approaching values for homozygotes suggested liver cell injury occurs before detectable in histological preparations

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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