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Phenotypes Associated with This Genotype
Genotype
MGI:3618112
Allelic
Composition		 Kcnmb4tm1Rwa/Kcnmb4tm1Rwa
Genetic
Background		 B6.129X1-Kcnmb4tm1Rwa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnmb4tm1Rwa mutation (0 available); any Kcnmb4 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal action potential ( J:103931 )
• dentate gyrus granule cells in brain slice culture show a gain-of-function for BK channels that sharpens action potentials and supports higher firing rates

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory