Phenotypes Associated with This Genotype

Genotype
MGI:3621019

• Allelic Composition: Etv1^tm2Tmj/Etv1⁺
• Genetic Background: involves: 129S1/Sv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal golgi tendon organ morphology ( J:75311 )

• distal hindlimb muscles show a 20-25% decrease in golgi tendon organ numbers

increased muscle spindle number ( J:75311 )

• distal hindlimb muscles show a 20-30% increase in spindle numbers

decreased pacinian corpuscle number ( J:107207 )

• 15-17% decrease in pacinian corpuscle numbers in the crus at P0-P1

abnormal dorsal root ganglion morphology ( J:75311 )

• about a 11% and 13% decrease in neuron numbers are seen in the L4 and L3 dorsal root ganglia, respectively

growth/size/body

decreased body size ( J:75311 )

• slightly smaller through the first 3 weeks of life

muscle

abnormal golgi tendon organ morphology ( J:75311 )

• distal hindlimb muscles show a 20-25% decrease in golgi tendon organ numbers

increased muscle spindle number ( J:75311 )

• distal hindlimb muscles show a 20-30% increase in spindle numbers