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Phenotypes Associated with This Genotype
Genotype
MGI:3625856
Allelic
Composition		 Foxa2tm1Jrt/Foxa2+
Nodaltm1Rob/Nodal+
Genetic
Background		 involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxa2tm1Jrt mutation (2 available); any Foxa2 mutation (28 available)
Nodaltm1Rob mutation (2 available); any Nodal mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal direction of embryo turning ( J:32935 )
• in embryos with loss of left-right asymmetry in Nodal expression the direction of turning is randomized
delayed embryo turning ( J:32935 )
• seen in all embryos

growth/size/body
situs ambiguus ( J:32935 )
• in 7 of 10 mutants the positioning of the abdominal viscera and heart is abnormal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory