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Phenotypes Associated with This Genotype
Genotype
MGI:3626196
Allelic
Composition		 Crebbptm2Pkb/Crebbptm2Pkb
Genetic
Background		 (B6.129-Crebbptm2Pkb x 129-Crebbptm2Pkb)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crebbptm2Pkb mutation (2 available); any Crebbp mutation (99 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, incomplete penetrance ( J:103607 )
• Background Sensitivity: about 25% of homozygotes survive to maturity on this background

growth/size/body
postnatal growth retardation ( J:103607 )
• surviving homozygotes are growth retarded

craniofacial
abnormal craniofacial morphology ( J:103607 )
• homozygotes that survive to maturity have craniofacial defects

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory