Phenotypes Associated with This Genotype

Genotype
MGI:3628918

• Allelic Composition: Capn2^tm1Pag/Capn2^tm1Pag
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:107240 )

• no homozygous embryos are found between E10.5 and E18.5; only 2/90 embryos isolated at E2.5 to 3.5 were homozygous

• no embryos examined at the 8-cell (blastocyst) stage are homozygous

embryo

abnormal preimplantation embryo development ( J:107240 )