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Phenotypes Associated with This Genotype
Genotype
MGI:3628919
Allelic
Composition		 Capn2tm1Pag/Capn2+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Capn2tm1Pag mutation (0 available); any Capn2 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:107240 )
• ratio of heterozygotes to wild-type offspring heavily favors heterozygotes; instead of 1:2 expected hets to wild-type, 23 wild-type to 176 heterosygotes is observed
• when mutant allele is maternally-derived, overrepresentation of heterozygotes is more pronounced than when mutant allele is transmitted by the male

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory