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Phenotypes Associated with This Genotype
Genotype
MGI:3629222
Allelic
Composition
Tlr4lps-2J/Tlr4lps-2J
Genetic
Background
BXD29-Tlr4lps-2J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tlr4lps-2J mutation (0 available); any Tlr4 mutation (92 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• in response to inhaled LPS, mice are unresponsive without increases in Tnfa and PMNs like other BXD RI strains


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory