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Phenotypes Associated with This Genotype
Genotype
MGI:3639862
Allelic
Composition		 Dfb/Dfb+
Genetic
Background		 involves: BALB/cByJ * BALB/cJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dfb mutation (1 available); any Dfb mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased or absent threshold for auditory brainstem response ( J:110189 )
• Background Sensitivity: decreased penetrance on mixed BALB and C57BL/6J background
• severe hearing loss with thresholds 20-40 dB above those of non-circling mice

nervous system
absent corpus callosum ( J:110189 )
• Background Sensitivity: drops to approximately 85% penetrance of acallosal phenotype in mixed BALB and C57BL/6J background

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory