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Phenotypes Associated with This Genotype
Genotype
MGI:3652734
Allelic
Composition		 B2mtm1Jae/B2mtm1Jae
Cd4tm1Jrp/Cd4tm1Jrp
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B2mtm1Jae mutation (8 available); any B2m mutation (121 available)
Cd4tm1Jrp mutation (0 available); any Cd4 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased CD8-positive, alpha-beta T cell number ( J:45168 )
• an increase in CD8+ T cells similar to that seen in single Cd4tm1Jrp mutants

immune system
increased CD8-positive, alpha-beta T cell number ( J:45168 )
• an increase in CD8+ T cells similar to that seen in single Cd4tm1Jrp mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory