About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3652791
Allelic
Composition
Apoetm1Unc/Apoetm1Unc
Timp1tm1Pds/Y
Genetic
Background
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (33 available); any Apoe mutation (158 available)
Timp1tm1Pds mutation (1 available); any Timp1 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• males fed an atherogenic, high-fat diet for 10 or 22 weeks develop a higher number of ruptures in the aortic media, in which all elastic laminae are digested and infiltrated with macrophages and form pseudo-microaneurysms, than single homozygous Apoetm1Unc mutant males


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/17/2024
MGI 6.24
The Jackson Laboratory