Phenotypes for Lig4 Xrcc5 MGI:3655987 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Xrcc5^tm1Dbr/Xrcc5⁺ Lig4^tm1Fwa/Lig4⁺
Genetic Background	involves: 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lig4^tm1Fwa mutation (1 available); any Lig4 mutation (44 available)
Xrcc5^tm1Dbr mutation (0 available); any Xrcc5 mutation (71 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

chromosome breakage ( J:80467 )

• cultured fibroblasts display chromosomal instability at a level of ~32%, similar to heterozygous Lig4 fibroblasts

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 06/12/2024 MGI 6.13