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Phenotypes Associated with This Genotype
Genotype
MGI:3687265
Allelic
Composition		 Aifm1tm2Pngr/Y
Tmem163Tg(ACTB-cre)2Mrt/0
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aifm1tm2Pngr mutation (0 available); any Aifm1 mutation (11 available)
Tmem163Tg(ACTB-cre)2Mrt mutation (3 available); any Tmem163 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:113016 )
• male mutants are present at Mendelian ratios at E7.5 and 10.5, but no viable embryos are recovered after E12.5

embryo
embryonic growth retardation ( J:113016 )
• embryos between E7.5 and 10.5 exhibit severe growth retardation

growth/size/body
embryonic growth retardation ( J:113016 )
• embryos between E7.5 and 10.5 exhibit severe growth retardation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory