Phenotypes Associated with This Genotype

Genotype
MGI:3695039

• Allelic Composition: Krt71^Mhdarco12/Krt71⁺
• Genetic Background: C3HeB/FeJ-Krt71^Mhdarco12

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Phenotype of Krt71^Mhdarco12/⁺ or Krt71^Mhdarco12/Krt71^Mhdarco12 and Krt71^Mhdarco13/⁺ or Krt71^Mhdarco13/Krt71^Mhdarco13 mice.

integument

waved hair ( J:116206 )

• curl visible by P10

• becomes less pronounced by 3 months of age

abnormal hair follicle inner root sheath morphology ( J:116206 )

• irregular formation of Henle's and Huxley's layers

• areas of increased thickness in Henle's layer are associated with round structures

• intermediate keratin filaments in Henle's layer form large whorls with short lengths of linear intermediate filament bundles

curly vibrissae ( J:116206 )