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Phenotypes Associated with This Genotype
Genotype
MGI:3695309
Allelic
Composition		 Atp2b2dfw-2J/Atp2b2+
Cdh23ahl/Cdh23ahl
Genetic
Background		 involves: CAST/Ei * BALB/cByJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp2b2dfw-2J mutation (1 available); any Atp2b2 mutation (66 available)
Cdh23ahl mutation (55 available); any Cdh23 mutation (281 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased or absent threshold for auditory brainstem response ( J:38429 )
• at 4 to 6 weeks of age, significantly elevated sound pressure thresholds
deafness ( J:38429 )
• show age-dependent hearing loss by 12 weeks of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory