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Phenotypes Associated with This Genotype
Genotype
MGI:3695937
Allelic
Composition
Gata3tm2Gsv/Gata3+
Genetic
Background
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S7/SvEvBrd * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata3tm2Gsv mutation (0 available); any Gata3 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• heterozygotes exhibit abnormal axonal navigation of the inner ear efferent neurons
• heterozygotes display aberrant inner ear efferent axonal projections, such as projections of fibers through the facial branchial motor nerve root, and caudal extension of efferent axons along the floor plate midline into r5 and occasionally into r6, not seen in wild-type littermates

cellular
• heterozygotes exhibit abnormal axonal navigation of the inner ear efferent neurons


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory