Phenotypes Associated with This Genotype

Genotype
MGI:3695937

• Allelic Composition: Gata3^tm2Gsv/Gata3⁺
• Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S7/SvEvBrd * C57BL/6)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal axon guidance ( J:66227 )

• heterozygotes exhibit abnormal axonal navigation of the inner ear efferent neurons

abnormal sensory neuron innervation pattern ( J:66227 )

• heterozygotes display aberrant inner ear efferent axonal projections, such as projections of fibers through the facial branchial motor nerve root, and caudal extension of efferent axons along the floor plate midline into r5 and occasionally into r6, not seen in wild-type littermates

cellular

abnormal axon guidance ( J:66227 )

• heterozygotes exhibit abnormal axonal navigation of the inner ear efferent neurons