Phenotypes Associated with This Genotype

Genotype
MGI:3696709

• Allelic Composition: Tg(Myh6-Camta2)1Eno/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:115868 )

• all die by 12 weeks of age due to heart failure

cardiovascular system

enlarged heart ( J:115868 )

cardiac hypertrophy ( J:115868 )

• hearts show extensive myocyte hypertrophy; hypertrophy worsens between 4 and 8 weeks of age

dilated cardiomyopathy ( J:115868 )

• by 9 weeks of age, hypertrophy progresses to dilated cardiomyopathy

congestive heart failure ( J:115868 )

• by 9 weeks of age, hypertrophy progresses to heart failure

muscle

dilated cardiomyopathy ( J:115868 )

• by 9 weeks of age, hypertrophy progresses to dilated cardiomyopathy

growth/size/body

enlarged heart ( J:115868 )

cardiac hypertrophy ( J:115868 )

• hearts show extensive myocyte hypertrophy; hypertrophy worsens between 4 and 8 weeks of age