About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3697177
Allelic
Composition
sevr/sevr
Genetic
Background
C3H/HeJ-sevr/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
sevr mutation (1 available); any sevr mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Characterization of the sevr/sevr mouse

mortality/aging
• high mortality rate at approximately 4 weeks of age

behavior/neurological
• slight tremors are often seen before death

growth/size/body
• smaller body size by 2 weeks of age

hearing/vestibular/ear
N
• ABR thresholds are normal

hematopoietic system
• between 5 weeks and 4 months of age there is atrophy of the thymus typical of that in wasting mice

immune system
• between 5 weeks and 4 months of age there is atrophy of the thymus typical of that in wasting mice

vision/eye
N
• opthalmoscopic examination shows normal eyes at 3 weeks of age

endocrine/exocrine glands
• between 5 weeks and 4 months of age there is atrophy of the thymus typical of that in wasting mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory