Phenotypes Associated with This Genotype

Genotype
MGI:3697816

• Allelic Composition: Camkk1^tm1Tch/Camkk1^tm1Tch
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal contextual conditioning behavior ( J:117630 )

• exhibit significantly less freezing at 24h and 10, 30, and 63 days in a long-term fear memory context test

• however, freezing in long term fear cued (tone) test is similar to wild-type, no difference in anxiety related behavior is found, and no motor defects are detected

nervous system

nervous system phenotype ( J:117630 )

N • basal synaptic transmission and long term potentiation in CA1 neurons are similar to wild-type

reproductive system

reproductive system phenotype ( J:117630 )

N • fertile