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Phenotypes Associated with This Genotype
Genotype
MGI:3699591
Allelic
Composition		 Sox10m2C3HeB/FeJ/Sox10m2C57BL/6J
Sox10Dom/Sox10Dom
Genetic
Background		 involves: C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox10Dom mutation (1 available); any Sox10 mutation (33 available)
Sox10m2C3HeB/FeJ mutation (0 available); any Sox10m2 mutation (0 available)
Sox10m2C57BL/6J mutation (0 available); any Sox10m2 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal intestine morphology ( J:117027 )
• increased gut length
aganglionic megacolon ( J:118320 )
• increased aganglionosis severity
• increased aganglionosis penetrance
• increased affected gut length

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory