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Phenotypes Associated with This Genotype
Genotype
MGI:3700926
Allelic
Composition		 Syne1tm1Rexu/Syne1tm1Rexu
Syne2tm1Rexu/Syne2+
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Syne1tm1Rexu mutation (0 available); any Syne1 mutation (202 available)
Syne2tm1Rexu mutation (0 available); any Syne2 mutation (297 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuromuscular synapse morphology ( J:118671 )
• phrenic nerve-diaphragm neuromuscular synapses have broader endplates than controls
abnormal phrenic nerve morphology ( J:118671 )
• phrenic nerve has significantly longer branches than controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory
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