Phenotypes for C1qa Sle16 MGI:3701668 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	C1qa^tm1Mjw/C1qa^tm1Mjw Sle16^{129S6/SvEvTac}/Sle16^C57BL/6
Genetic Background	involves: 129S/SvEv * 129X1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
C1qa^tm1Mjw mutation (1 available); any C1qa mutation (22 available)
Sle16^{129S6/SvEvTac} mutation (0 available); any Sle16 mutation (0 available)
Sle16^C57BL/6 mutation (0 available); any Sle16 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased susceptibility to systemic lupus erythematosus ( J:118645 )

increased anti-nuclear antigen antibody level ( J:118645 )

increased anti-chromatin antibody level ( J:118645 )

increased anti-double stranded DNA antibody level ( J:118645 )

increased anti-single stranded DNA antibody level ( J:118645 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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