Phenotypes for Erap1 Tap1 MGI:3706235 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Erap1^tm1Nsha/Erap1^tm1Nsha Tap1^tm1Arp/Tap1^tm1Arp
Genetic Background	B6.129-Erap1^tm1Nsha Tap1^tm1Arp

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Erap1^tm1Nsha mutation (0 available); any Erap1 mutation (59 available)
Tap1^tm1Arp mutation (4 available); any Tap1 mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal antigen presentation via MHC class I ( J:112389 )

• processing of certain antigenic precursors in the ER is defective in mutant splenocytes, because Arts functions as a unique protease

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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