Phenotypes Associated with This Genotype

Genotype
MGI:3706520

• Allelic Composition: Casp8^tm1.1Yuan/Casp8^tm1.1Yuan
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * MF1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:49459 )

• homozygotes exhibit no differences from homozygous Casp8^tm1Yuan mutants in the kinetics of prenatal death, however no data is presented in J:49459

cardiovascular system

abnormal myocardium layer morphology ( J:49459 )

abnormal blood circulation ( J:49459 )

• homozygotes show no differences in the gross phenotype from homozygous Casp8^tm1Yuan, however no data is presented in J:49459

growth/size/body

decreased embryo size ( J:49459 )

embryo

decreased embryo size ( J:49459 )

hematopoietic system

abnormal hematopoietic system morphology/development ( J:49459 )

muscle

abnormal myocardium layer morphology ( J:49459 )