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Phenotypes Associated with This Genotype
Genotype
MGI:3706898
Allelic
Composition		 Jak2tm1Kf/Jak2tm1Kf
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak2tm1Kf mutation (0 available); any Jak2 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:112700 )
• homozygous embryos die in utero by or before ~12.5 dpc (days post coitum)

embryo
decreased embryo size ( J:112700 )
• homozygous embryos are smaller than wild-type or heterozygotes

growth/size/body
decreased embryo size ( J:112700 )
• homozygous embryos are smaller than wild-type or heterozygotes

hematopoietic system
abnormal erythropoiesis ( J:112700 )
• embryos lack definitive erythropoiesis, resulting in lethality

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory