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Phenotypes Associated with This Genotype
Genotype
MGI:3709889
Allelic
Composition		 Tcf12tm1Zhu/Tcf12tm2Zhu
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf12tm1Zhu mutation (0 available); any Tcf12 mutation (75 available)
Tcf12tm2Zhu mutation (0 available); any Tcf12 mutation (75 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
arrested T cell differentiation ( J:120411 )
• T cell development can proceed to the ISP stage but not to the single positive (SP) stage

immune system
arrested T cell differentiation ( J:120411 )
• T cell development can proceed to the ISP stage but not to the single positive (SP) stage

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory