Phenotypes for Onecut2 Onecut3 MGI:3711874 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Onecut2^tm1Flem/Onecut2^tm1Flem Onecut3^tm1Jqmn/Onecut3^tm1Jqmn
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * Swiss

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Onecut2^tm1Flem mutation (0 available); any Onecut2 mutation (21 available)
Onecut3^tm1Jqmn mutation (0 available); any Onecut3 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:121610 )

N	• pancreas organogenesis is normal at all stages in double homozygotes • at E14.5 and E18.5, expression of Neurog3, insulin, and glucagons is comparable to wild-type embryos; endocrine differentiation is normal • enteroendocrine cells differentiate normally

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24