Phenotypes for Ppm1b MGI:3713230 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ppm1b^tm1.1Tamu/Ppm1b^tm1.1Tamu
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppm1b^tm1.1Tamu mutation (1 available); any Ppm1b mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:121900 )

• most conceptuses die between the two-cell and eight-cell stages; no homozygous embryos are found between E7.5 and 13.5, and reduced numbers are found in litters from E1.5 to E3.5

embryo

abnormal embryonic tissue morphology ( J:121900 )

• majority of homozygous embryos identified from E1.5 to E3.5 show abnormal morphology

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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