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Phenotypes Associated with This Genotype
Genotype
MGI:3714395
Allelic
Composition
Myf5tm1Jae/Myf5+
Myf6tm1Thbr/Myf6+
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myf5tm1Jae mutation (1 available); any Myf5 mutation (17 available)
Myf6tm1Thbr mutation (0 available); any Myf6 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• double heterozygous mice that carry the Myf5 and Myf6 alleles on different chromosomes and express drastically reduced levels of Myf5 mRNA do not survive to weaning and when delivered by cesarean section at E18.5, the pups die within a few minutes after delivery

skeleton
• mutants lack the distal parts of the ribs
• the average rib length is between that of Myf6 and Myf5 homozygotes


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory