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Phenotypes Associated with This Genotype
Genotype
MGI:3715269
Allelic
Composition		 Gfra1tm2.1Jmi/Gfra1tm2.1Jmi
Genetic
Background		 involves: 129/Sv * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfra1tm2.1Jmi mutation (1 available); any Gfra1 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:122607 )
• phenotype is stated to be identical to that of Gfra1tm1Jmi homozygotes

nervous system
abnormal enteric nervous system morphology ( J:122607 )
• enteric nervous system is completely absent in embryos examined at E15.5

renal/urinary system
absent kidney ( J:122607 )
• homozygotes lack kidneys

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory