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Phenotypes Associated with This Genotype
Genotype
MGI:3718440
Allelic
Composition		 Unc13atm2Bros/Unc13a+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc13atm2Bros mutation (0 available); any Unc13a mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:108689 )
N
• mice have normal glucose tolerance

endocrine/exocrine glands
abnormal pancreatic islet morphology ( J:108689 )
• mice exhibit a reduction in the size of ready releasable pools (RRPs) of vesicles in islet cells and do not respond to PMA (12-myristate 13-acetate ester) treatment

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory