Phenotypes for Mapkapk5 Tg(SV40-NRAS*G12D)1Sco MGI:3757991 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mapkapk5^tm1Pqs/Mapkapk5^tm1Pqs Tg(SV40-NRAS*G12D)1Sco/?
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapkapk5^tm1Pqs mutation (0 available); any Mapkapk5 mutation (30 available)
Tg(SV40-NRAS*G12D)1Sco mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased lymphoma incidence ( J:117893 )

• lymphomagenesis is enhanced in the few surviving mice relative to in Tg(SV40-NRAS*G12D)1Sco mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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