Phenotypes for Mapkapk5 Tg(SV40-NRAS*G12D)1Sco MGI:3757992 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mapkapk5^tm1Pqs/Mapkapk5⁺ Tg(SV40-NRAS*G12D)1Sco/?
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapkapk5^tm1Pqs mutation (0 available); any Mapkapk5 mutation (31 available)
Tg(SV40-NRAS*G12D)1Sco mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased lymphoma incidence ( J:117893 )

• lymphomagenesis is enhanced relative to in Tg(SV40-NRAS*G12D)1Sco mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24