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Phenotypes Associated with This Genotype
Genotype
MGI:3758622
Allelic
Composition
Il20rbtm1Dnax/Il20rbtm1Dnax
Genetic
Background
B6.129-Il20rbtm1Dnax
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il20rbtm1Dnax mutation (0 available); any Il20rb mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice do not exhibit epidermal hyperplasia in response to intradermal IL-23 treatment as do wild-type mice
• however, following treatment with IL-23 the numbers of CD4+ T cells, CD11c+ dendritic cells, F4/80+ macrophage, and neutrophils are increased as in wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory