Phenotypes Associated with This Genotype

Genotype
MGI:3758632

• Allelic Composition: Gdf5^Rgsc451/Gdf5⁺
• Genetic Background: C57BL/6JJcl-Gdf5^Rgsc451

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

brachypodia ( J:125122 )

abnormal phalanx morphology ( J:125122 )

• the proximal and middle phalanges are short and fused

• however, the lengths of the distal phalanges and metacarpal/metatarsal bones are normal

skeleton

abnormal phalanx morphology ( J:125122 )

• the proximal and middle phalanges are short and fused

• however, the lengths of the distal phalanges and metacarpal/metatarsal bones are normal

abnormal cartilage morphology ( J:125122 )

• at 8 weeks, the peripheral (finger/toe) joints in 1 of 3 mice exhibits mild degeneration in the distal interphalangeal joint

fused joints ( J:125122 )

• the metacarpo-/metatarso-phalanges joints are fused